Around 150 Britons being flown back to the UK from the coronavirus-hit city of Wuhan on Sunday will be quarantined at a facility in Milton Keynes.
Everyone boarding the plane at the Chinese city, which is the epicentre of the outbreak, will be assessed and continue to be monitored after landing in the UK on Sunday morning.
Kents Hill Park, a conference centre and hotel, will be used to house the returning citizens after they land at RAF Brize Norton, South Central Ambulance Service has said.
The individuals will remain at the site in isolation for 14 days.
The ambulance service said the presence of the group in Milton Keynes, Buckinghamshire, does not present a risk to local people.
“The local site has been chosen because it offers appropriate accommodation and other facilities for those coming back from Wuhan while they stay in Milton Keynes,” the ambulance service said.
“It also allows their health to be regularly monitored and has the necessary medical facilities close at hand should they be required.”
All staff working at the facility will wear appropriate protective equipment at all times.
Foreign secretary Dominic Raab said the flight would be the final service chartered by the Foreign Office to bring UK nationals back from the Chinese city
Britons who returned on a flight last month were taken to Arrowe Park Hospital on the Wirral.
The global death toll from the ongoing outbreak has reached 724, priming the illness to become more deadly than SARS.
Another 81 fatalities have been recorded in Hubei province in China, where Wuhan - the city where the infection was first reported is located.