Doctors leaders have passed a vote of no confidence in health secretary Jeremy Hunt.
Representatives at the British Medical Association's (BMA) annual representative meeting in Edinburgh passed the motion with an "overwhelming majority".
Presenting the motion, Dr Jacky Davis said that Hunt was leading the Government's "ideological attack on the service and on staff".
Hunt became Health Secretary following a cabinet reshuffle in September.
The union, which represents more than 150,000 doctors and medical students, also voted no confidence in his predecessor Andrew Lansley at last year's meeting.
Dr Davis said the NHS had been "wrecked" by the Government, adding: "Leading the attack (on the health service) has been the Health Secretary.
"His main purpose seems to be criticising the service and undermining the staff.
"He is at the forefront of a new political blame game, blaming frontline NHS staff for the predictable chaos resulting from his Government's reforms and cuts."