The Champions League quarter-final draw will take place at 11:00 GMT on Friday.
English champions Manchester United and Chelsea could be drawn against each other three years on from their last eight meeting, when United prevailed 3-1 on aggregate en route to the 2011 Wembley final.
With no seedings applied from the last eight, United or Chelsea face the prospect of being paired with one of European football's elite sides.
Spain are represented by Real Madrid, Barcelona and Atlético Madrid, while finalists Bayern Munich and Borussia Dortmund are also in the mix.
Paris Saint-Germain round up the eight sides attempting to reach the Lisbon final on 24 May. It is the first time all eight seeded sides which topped their group are in the quarter-finals.
The quarter-final first legs will be staged on 1 and 2 April, with the second legs played the following week on 8 and 9 April.