Drug To 'Switch Off Hunger' May Be Available In The Future Thanks To New Brain Research
Have Scientists Found A Way To Switch Off Hunger?
Rachel Moss— The Huffington Post UK
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Just thinking about food makes us feel hungry, which can be a bit of a pain if we're trying to kickstart weight loss.
But scientists may now have found a way to "switch off" our sense of hunger.
Researchers from Harvard Medical School and Edinburgh University have identified the brain cells which create the sensation of hunger.
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By targeting weight loss drugs at this brain circuit - known as melanoncortin 4 receptor-regulated (MC4R) - the scientists believe they may be able to offer support for people trying to lose weight.
The researchers altered the MC4R cells in a group of mice and saw a change in the amount amount of food they ate. This indicates that their desire to eat had been altered.
Drugs that alter the hunger sensation are not currently available, so for now the most effective way to manage appetite may be to eat foods that help you feel fuller for longer.
Check out the slideshow below to see how else foods influence your appetite.
12 Foods That Control Your Appetite
Apples(01 of12)
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Chomp on an apple approximately a half hour before a meal -- the fiber and water from the apple will fill you up, so you'll eat less, says Debra Wein, RD, president of Wellness Workdays, a leading provider of worksite wellness programs. (credit:Getty Images)
Avocados(02 of12)
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Eating half of an avocado with your lunch may help you feel full for the rest of the afternoon, according to a study published in Nutrition Journal. Women who did that felt 22 percent more satisfied and had a 24 percent lower desire to snack three hours later than on days they ate a calorically equivalent lunch without the avocado. (credit:Flickr:Elin Schönfelder)
Beans, Chickpeas & Lentils(03 of12)
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Dietary pulses such as chickpeas, lentils, beans and peas are protein-rich superfoods that also pack in fiber, antioxidants, B vitamins and iron. Eating more of them may also help you control your appetite. A recent meta-analysis published in the journal Obesity found that people were 31 percent more satisfied after a meal when it included pulses. (credit:Flickr:jfl1066)
Soup(04 of12)
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In a Penn State study, people who slurped a bowl of low-calorie, broth-based soup before their lunch entrées reduced their total calorie intake at the meal by 20 percent. "Soups can take the edge of your appetite since they take up a lot of volume in your stomach, but with very few calories," says Beth Saltz, RD, owner of nutritionskitchen.com. (credit:Flickr:Gary Soup)
Pickles(05 of12)
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Pickles, sauerkraut, kimchi and other fermented foods have short-chain fatty acids (SCFAs), and recent research in the Annals of The New York Academy of Sciences found that they help strengthen the bond between the gut and the brain. SCFAs stimulate production of hormones that cross the blood-brain barrier and improve appetite signaling. Fermented foods also boast probiotics, the healthy bacteria that help digestion. Some experts believe probiotics may reduce appetite and aid weight loss, though research is inconclusive. (credit:Flickr:соннна.тетеря)
Chili Powder(06 of12)
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You may already know that capsaicin, the compound in chilis that gives them their kick, fires up your metabolism. Recent research from Maastricht University in the Netherlands shows that adding heat to your meal may also control your appetite. The study, which was published in the journal Appetite, found that adding 1/4 teaspoon of chili pepper to each meal increased satiety and fullness. What's more, some participants were only allowed to consume 75 percent of their recommended daily calorie intake, but didn't feel any more desire to continue eating after dinner than those who were given 100 percent of their daily calories. (credit:Getty Images)
Dark Chocolate(07 of12)
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When you're craving something sweet, reach for dark chocolate. Research suggests dark chocolate can help reduce blood pressure and protect the heart and brain. It's also more filling than milk chocolate and may help curb cravings for both sweet and salty foods, according to a study in the journal Nutrition & Diabetes. In fact, participants consumed 17 percent fewer calories at a meal following a dose of dark chocolate. (credit:Flickr:www.schoko-riegel.com)
Eggs(08 of12)
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Starting your day with eggs will leave you satisfied until lunch. The power's in the protein: research from the University of Missouri at Columbia suggests that eating a 300-calorie breakfast made up of 30 to 39 grams of protein (think: eggs and sausage) reduces hunger pangs and increases fullness during the time between breakfast and lunch. What's more, the research revealed that high-protein breakfast eaters consume fewer calories throughout the day. (credit:Getty Images)
Nuts(09 of12)
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Nuts are another filling food that may help you eat less. In a British Journal of Nutrition study, obese women who paired either 1.5 ounces of peanuts or 3 tablespoons of peanut butter with Cream of Wheat cereal and orange juice felt fuller for up to 12 hours after finishing breakfast than those who didn't eat the peanut products. "Nuts are essentially designed by nature to control appetite because they're rich in healthy unsaturated fat, along with bonus protein and fiber," says Cynthia Sass, MPH, RD, Health magazine contributing nutrition editor. Together, the three nutrients slow digestion and regulate blood sugar when combined with carbs like fruit, oatmeal or brown rice. (credit:Getty Images)
Oatmeal(10 of12)
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Consider ditching cereal for warm, gooey oatmeal. Oatmeal will keep you feeling fuller longer, suggests a study in the Journal of the American College of Nutrition. Participants were served 250 calories of cereal or oatmeal with 113 calories of milk. The oatmeal-eaters were satiated longer, and they also experienced a greater reduction in hunger and a decreased desire to eat compared to ready-to-eat cereal eaters. Why the difference? Oatmeal is higher in fiber and protein and also has higher amounts of beta-glucan -- the sugars that give oatmeal its heart-healthy properties, hydration and molecular weight compared to ready-to-eat cereals. (credit:Getty Images)
Water(11 of12)
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Being low on H2O can trick you into believing you're hungry. Why? The symptoms of hunger are similar to those of being dehydrated: low energy, reduced cognitive function, and poor mood. So next time you're craving an afternoon snack, drink a tall glass of water and wait 10 minutes. Chances are, your hunger pangs will pass, and you'll have saved hundreds of calories. (credit:Getty Images)
Whey Protein(12 of12)
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Dairy whey -- one of the two proteins that make up milk products -- may be the most filling type of protein. According to a study published in the journal Appetite, people who drank whey protein ate 18 percent less two hours later than those who had consumed a carbohydrate drink. Use whey protein powder to give smoothies a protein punch. (credit:Getty Images)