Andrew Neil is known for being fairly unflappable when it comes to interviewing.
But the veteran broadcaster was left looking utterly nonplussed while questioning a well-known conspiracy theorist on his view on 9/11 and that the Royal family are in fact shape-shifting lizards.
Speaking on BBC1's This Week, Neil incredulously questioned David Icke on his views.
He asked: "Do you still think the Royal Family were shape shifting lizards?"
Icke answered firmly: "Yes, I do."
Neil continued: "You also want us to believe that 9/11 is a conspiracy?"
Again, Icke responded: "Yes."
The bemused presenter said: “I can see the point that you might that you have some questions about 9/11 but if you also think that Buckingham Palace is inhabited by lizards, it kind of undermines you.”
But Icke defended his views saying: “It’s not that simple. The whole big back story before you get to what I’m saying, if you deliver it in one line - 'the world is run by reptiles' - you meet on one level.
“'Oh that’s crazy', immediate reaction.
“But when you see the back story and the evidence to support this, ancient and modern, you see that one throwaway line in a completely different context.”
Conspiracy theories hit the headlines earlier this week when George Osborne dismissed the idea that there was a "conspiracy" against the Leave campaign.
A former professional goalkeeper and television presenter, Icke gained international notoriety in the 1990s when he claimed a race of shape-shifting lizards were masquerading as Presidents and monarchs.
More memorable among British audiences was his appearance on the late Sir Terry Wogan’s chat show, where he contended he was the son of God.
Earlier this year he came out in favour of leaving the European Union, labelling the bloc a “dictatorship”.