REM Sleep Disorder ‘May Be Early Warning Sign For Parkinson’s And Dementia’

'Diagnosing REM disorders may allow us to provide individuals with preventative actions to keep them healthy.'

Acting out dreams and lashing out in your sleep could be an early warning sign for ailments such as Parkinson’s disease or dementia, researchers have said.

People who suffer from REM sleep behaviour disorder may physically move limbs when dreaming. They may also talk, shout, hit or punch, according to the National Sleep Foundation.

New research has found a link between the dreaming condition and development of a group of neurodegenerative diseases later in life.

More than 80% of people who suffer from REM sleep disorder eventually develop conditions such as Parkinson’s disease and dementia with Lewy bodies, Dr John Peever of the University of Toronto, Canada, said.

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The brain stem has been known since the 1960s to be involved in controlling dreaming during rapid eye movement sleep (REM), when vivid dreams occur.

Dr John Peever has since discovered the cells responsible for the dream state - called REM-active neurons. His team have learned how to control the cells in rodents, and in the process, dreaming.

They can “switch on” the cells to cause a rapid transition into REM sleep, he said.

The team used the knowledge to examine dreaming dysfunctions such as REM sleep behaviour disorder in humans.

Dr Peever said: “Our research suggests sleep disorders may be an early warning sign for diseases that may appear some 15 years later in life."

Dr Peever, who presented his results at the 2017 Canadian Neuroscience Meeting, the annual meeting of the Canadian Association for Neuroscience - Association Canadienne des Neurosciences (CAN-ACN), hopes it will eventually allow for the development of protective strategies for people who may go on to develop the conditions.

“Much like we see in people prone to cancer, diagnosing REM disorders may allow us to provide individuals with preventative actions to keep them healthy long before they develop these more serious neurological conditions,” he said.