The audience member used a question on the late-night debate programme to criticise Health Secretary Jeremy Hunt and challenge the connection between junior medics and weekend fatalities. Watch video, above.
Addressing Tory Welsh Secretary Stephen Crabb, the doctor said: "I qualified in medicine in 1976 and you're quite right to point out that there have been a number of difficulties with secretary of states since that time.
"Over the last 40 years none have had such a lack of respect as the current secretary of state Mr Hunt."
The man then addressed links made between the rise in deaths within the NHS at weekends and hard-working junior medics.
He said: "Mr Hunt has at best been disingenuous - as (Nigel) Farage has pointed out, there is a rise in deaths at the weekend - but there is nothing proven to show that is due to a lack of junior doctors at that time.
"It's multi-factorial, they work hard seven days a week, and by imposing this contract on them will, I hope, solve the serious recruitment problem we have here in Wales."
Wales will not be affected by the imposition of the new contract, which will only affect junior medics in England.
Thursday night's Question Time came from Llanelli, Wales and included as panelists Conservative Secretary of State for Wales Stephen Crabb, First Minister of Wales Labour's Carwyn Jones, Plaid Cymru leader Leanne Wood, Ukip leader Nigel Farage and comedian Romesh Ranganathan.