The Met Office has issued a severe weather alert across large swathes of the country as snow, rain, sleet and thunder threaten to blight our skies.
Cloud and sleet showers are forecast for Friday with widespread frost developing overnight in London and South East England as temperatures dip to -5 °C.
Saturday will see scattered showers, some wintry, while Sunday will see much of the same – along the possibility of “prolonged” snow and widespread overnight frosts.
The Met Office website said: "There is a 90% probability of severe cold weather/icy conditions until noon on Monday in parts of England.
"Increasingly cold air will spread from the North West across England on Thursday night and during Friday, with showers turning more wintry from the north.
"Average temperatures are expected to continue falling through the weekend, with a northerly airstream likely to be established by Sunday.
"Frost and ice are expected to become increasingly widespread through the period, with some severe overnight frosts likely in the north over any snow cover by Monday."
The weather could increase the health risks to vulnerable patients and disrupt the delivery of services.
Public Health England (PHE) have urged people to help vulnerable family and friends to keep warm.
Dr Angie Bone of PHE's extreme events team, said: "Cold does kill, even in places where the temperatures aren't at their lowest. Most of our advice on keeping warm in cold weather may seem like common sense, but it's important that we make the point that people should think about how cold can affect them.
"Our advice is that when indoors, have plenty of warm food and drinks to stay warm and try to maintain indoor temperatures to at least 18C, particularly if you are not mobile, have long-term illness or are 65 or over.
"This is also a good time to think about how the bad weather may affect your friends and family, particularly if they are older or very young or have pre-existing health conditions. These groups can be particularly vulnerable to the ill-effects of cold so think now what you could do to help."