The duo are taking over after Philip and Holly left last year.
The daytime show has been without a permanent host since the departures of Phillip Schofield and Holly Willoughby.
And the presenter got in on the fun herself, too.
"Cat is like a breath of fresh air..."
The famous blue sofa will welcome a new face next week, alongside Rylan Clark and Craig Doyle.
Cat Deeley joined the duo for a new instalment of the Friends parody that featured throughout their time on SM:TV Live
The duo reunited with Cat Deeley last year for the documentary The Story Of SM:TV.
The comedian was on fine form during an appearance on Radio 2, his first in eight months.
"It wasn’t great for the first couple of months... We got it wrong initially," Ant recalled.
No word yet on whether Wonky Donkey has been brought out of retirement, though.