Denise van Outen
The actor and presenter appeared on the BBC soap in 2015.
The iconic Channel 4 breakfast show celebrates its 30th anniversary next year.
Jason Donovan recently became the seventh cast member to withdraw from the show, following Hamish Gaman, Joe-Warren Plant and Denise Van Outen.
The professional skater injured his hand while putting on his sock ahead of last week's live show.
Denise Van Outen and Rufus Hound have already had to withdraw from the ITV skating competition.
The pair were "like brother and sister" when they hosted The Big Breakfast in the 1990s.
She has since quit the series on medical grounds after finding out she'd fractured her shoulder.
She and professional partner Matt Evers are out of the ITV skating competition.
The TV personality was rehearsing for Sunday's launch show when she "went flying" and injured herself.
Denise Van Outen's grand reveal didn't go quite to plan.