The 24-year-old also said she was "not having as much fun" at the Summer Olympics in Tokyo.
The Loose Women star said Piers' comments “prove why so many people suffer in silence” with their mental health.
The tennis legend's answer on how she deals with media pressure has left people obsessed.
Alexandria Ocasio-Cortez, Steph Curry, Serena Williams and others rallied around Osaka, who opened up about her struggles with mental health.
"Big words from someone who flounced off set because the weatherman gave them a talking to."
The four-time Grand Slam champion was fined a day earlier for her decision to boycott the media during the major tennis tournament.
Barack Obama has backed the move by big names including Naomi Osaka and LeBron James.
The cartoon was widely criticised last year.
"Disgusted, but not surprised."
Serena Williams was defeated in the first round of the Miami Open on Wednesday, but the tennis superstar is still proud of how far she’s come.