Rumours have been rife about behind-the-scenes tension on the daytime show, which ITV has repeatedly denied.
The pair are thought to have beef stemming back to the 2016 Golden Globes.
The morning after the National Television Awards is always a tough one for Holly and co-presenter Phillip Schofield.
The former Love Island star was involved in a confrontation with a photographer after Tuesday night's National Television Awards.
Denise Welch walked out early, while Nadia Sawalha appeared to say she "wasn't happy" about losing out.
The GMB host boycotted this year's bash but still had a lot to say from the comfort of his sofa.
With David Walliams in charge of proceedings, there were plenty of talking points.
Piers Morgan also branded the quip "nasty" on Twitter, where the comment was also negatively received.
Ant and Dec won Best Presenter for the 19th consecutive year.
"Yet another example of why the British public shouldn't be allowed to vote for things," wrote one Twitter user.