The Champions League quarter-final draw will take place at 11:00 GMT on Friday.
English champions Manchester United and Chelsea could be drawn against each other three years on from their last eight meeting, when United prevailed 3-1 on aggregate en route to the 2011 Wembley final.
With no seedings applied from the last eight, United or Chelsea face the prospect of being paired with one of European football's elite sides.
In the mix: But who will draw who in the last eight?
Spain are represented by Real Madrid, Barcelona and Atlético Madrid, while finalists Bayern Munich and Borussia Dortmund are also in the mix.
Paris Saint-Germain round up the eight sides attempting to reach the Lisbon final on 24 May. It is the first time all eight seeded sides which topped their group are in the quarter-finals.
The quarter-final first legs will be staged on 1 and 2 April, with the second legs played the following week on 8 and 9 April.
United v Olympiakos
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Manchester United's Dutch striker Robin van Persie celebrates scoring his third goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
Soccer - UEFA Champions League - Round of 16 - Second Leg - Manchester United v Olympiakos - Old Trafford(02 of44)
General view of an empty stand in front of a banner reading 'The Chosen One' and an image of David Moyes (credit:PA)
Soccer - UEFA Champions League - Round of 16 - Second Leg - Manchester United v Olympiakos - Old Trafford(03 of44)
Manchester United's Robin van Persie is fouled by Olympiakos' Jose Holebas (left) to earn his side a penalty (credit:PA)
Soccer - UEFA Champions League - Round of 16 - Second Leg - Manchester United v Olympiakos - Old Trafford(04 of44)
Manchester United's Robin van Persie is fouled by Olympiakos' Jose Holebas (left) to earn his side a penalty (credit:PA)
Soccer - UEFA Champions League - Round of 16 - Second Leg - Manchester United v Olympiakos - Old Trafford(05 of44)
Manchester United's Robin van Persie is fouled by Olympiakos' Jose Holebas (left) to earn his side a penalty (credit:PA)
Soccer - UEFA Champions League - Round of 16 - Second Leg - Manchester United v Olympiakos - Old Trafford(06 of44)
Manchester United's Wayne Rooney (left) grabs the match ball as team-mate Robin van Persie celebrates scoring their first goal of the game from the penalty spot (credit:PA)
Soccer - UEFA Champions League - Round of 16 - Second Leg - Manchester United v Olympiakos - Old Trafford(07 of44)
Manchester United's Robin van Persie celebrates scoring their first goal of the game from the penalty spot (credit:PA)
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Olympiakos' Paraguayan midfielder Hernan Perez (L) and Manchester United's French defender Patrice Evra vie for the ball during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Olympiakos' Greek defender Kostas Manolas (L) and Manchester United's English striker Danny Welbeck vie for the ball during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (L) celebrates scoring the second goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Olympiakos' Paraguayan midfielder Hernan Perez (R) and Olympiakos' Brazilian defender Leandro Salino (L) close in on Manchester United's French defender Patrice Evra during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Former Manchester United manager Sir Alex Ferguson arrives for the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Manchester United's English defender Phil Jones (C) vies with Olympiakos' Brazilian defender Leandro Salino during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/ANDREW YATES (Photo credit should read ANDREW YATES/AFP/Getty Images) (credit:Getty Images)
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Manchester United's English defender Phil Jones (R) vies with Olympiakos' Brazilian defender Leandro Salino during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/ANDREW YATES (Photo credit should read ANDREW YATES/AFP/Getty Images) (credit:Getty Images)
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Olympiakos' Greek defender Jose Holebas (R) vies with Manchester United's Brazilian defender Rafael during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/ANDREW YATES (Photo credit should read ANDREW YATES/AFP/Getty Images) (credit:Getty Images)
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Olympiakos' Costa Rican forward Joel Campbell (R) vies with Manchester United's English defender Phil Jones during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/ANDREW YATES (Photo credit should read ANDREW YATES/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(17 of44)
MANCHESTER, ENGLAND - MARCH 19: Phil Jones of Manchester United competes with Joel Campbell of Olympiacos during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(18 of44)
MANCHESTER, ENGLAND - MARCH 19: Patrice Evra of Manchester United competes with Hernan Perez of Olympiacos during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(19 of44)
MANCHESTER, ENGLAND - MARCH 19: Patrice Evra of Manchester United competes with Hernan Perez of Olympiacos during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie takes a penalty to score the opening goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(21 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United scores the opening goal from a penalty kick during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Olympiakos' Greek defender Jose Holebas (R) fouls Manchester United's Dutch striker Robin van Persie during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (L) celebrates scoring the second goal with teammate English striker Wayne Rooney during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(24 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(25 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal with his team-mates during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(26 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United scores the third goal from a free-kick to complete his hat-trick during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Manchester United manager David Moyes runs from the pitch at halt time during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/ANDREW YATES (Photo credit should read ANDREW YATES/AFP/Getty Images) (credit:Getty Images)
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Manchester United's Spanish goalkeeper David de Gea (2-R) makes a double save during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(29 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal with his team-mates during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Manchester United's Dutch forward Robin van Persie (2-L) scores his teams second goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/ANDREW YATES (Photo credit should read ANDREW YATES/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(31 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal with his team-mates during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (L) celebrates scoring the second goal with teammate English striker Wayne Rooney during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (2-R) celebrates scoring the second goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(34 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal with his team-mates during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (L) celebrates scoring the second goal with teammate English midfielder Michael Carrick (C) during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (C) celebrates scoring his third goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(37 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the opening goal from a penalty kick during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (L) celebrates scoring the second goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(39 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal with his team-mates during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(40 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(41 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal with his team-mates during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(42 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the third goal from a free-kick to complete his hat-trick during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
Manchester United v Olympiacos FC - UEFA Champions League Round of 16(43 of44)
MANCHESTER, ENGLAND - MARCH 19: Robin van Persie of Manchester United celebrates scoring the second goal with his team-mates during the UEFA Champions League Round of 16 second round match between Manchester United and Olympiacos FC at Old Trafford on March 19, 2014 in Manchester, England. (Photo by Laurence Griffiths/Getty Images) (credit:Getty Images)
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Manchester United's Dutch striker Robin van Persie (R) celebrates scoring his third goal during the UEFA Champions League round of 16 second leg football match between Manchester United and Olympiakos at Old Trafford in Manchester on March 18, 2014. AFP PHOTO/PAUL ELLIS (Photo credit should read PAUL ELLIS/AFP/Getty Images) (credit:Getty Images)