It's hard to believe that the very first Comic Relief Red Nose Day took place 25 years ago, on 5 February 1988. In honour of this milestone, and Red Nose Day on Friday 15 March, we've put together a gallery of memorable moments - both celebrity and not.
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From the Spice Girls to One Direction, from 'Celebrity Fame Academy' to Samantha Cameron: take a trip down memory lane with our gallery of 100 photos below - and watch some of Comic Relief's funniest moments here.
25 Years Of Red Nose Day
Kylie and Jason(01 of100)
Lenny Henry, Angus Deayton and Richard Fairbrass(02 of100)
Jennifer Saunders and Tony Robinson(03 of100)
Michael Caine and Ben Kingsley(04 of100)
Prince Andrew(05 of100)
Delia Smith and Dawn French(06 of100)
Jeffrey Archer(07 of100)
The England rugby team(08 of100)
Corncorde(09 of100)
The Spice Girls(10 of100)
Jonathan Ross(11 of100)
Ballykissangel's Dervla Kirwan and Stephen Tompkinson(12 of100)
Mariella Frostrup, David Baddiel, Nick Hancock and Jenny Agutter(13 of100)
Eternal(14 of100)
Kathy Burke, Dawn French and Jennifer Saunders (as the Spice Girls)(15 of100)
Stars of The Archers(16 of100)
Paul Gascoigne and Chris Evans(17 of100)
Geri Halliwell(18 of100)
Emma Freud and Gordon Brown(19 of100)
All Saints(20 of100)
Tamzin Outhwaite(21 of100)
Robbie Williams(22 of100)
Lenny Henry and Steve Redgrave(23 of100)
Ruby Wax, Emma Freud and Sally Phillips(24 of100)
Lady Victoria Hervey and Sophie Anderton(25 of100)
Billie Piper and Nick Hancock(26 of100)
The first Celebrity Big Brother contestants(27 of100)
Chris Eubank(28 of100)
David Baddiel, Ainsley Harriott and Angus Deayton(29 of100)
A red nose Tube train(30 of100)
A red nose on Number 10, Downing Street(31 of100)
Dawn French and Tony Blair(32 of100)
Gareth Gates(33 of100)
Graham Norton and Angellica Bell(34 of100)
Gordon Ramsay(35 of100)
Gary Lineker(36 of100)
Lenny Henry and JK Rowling(37 of100)
Angus Deayton(38 of100)
First Celebrity Fame Academy contestants John Thomson, Ulrikka Jonsson and Fearne Cotton(39 of100)
Ruby Wax(40 of100)
Jo Brand(41 of100)
Patrick Kielty and Cat Deeley(42 of100)
Doon Mackichan(43 of100)
Kwame Kwei-Armah (44 of100)
Police recruits at Hendon(45 of100)
Troops in the Kuwait desert(46 of100)
Celebrity fun-runners(47 of100)
A red nose wedding(48 of100)
Saracens' Richard Hill (49 of100)
Phil Collins(50 of100)
Elle MacPherson and Matt Lucas(51 of100)
Davina McCall(52 of100)
Kenzie and John McCririck(53 of100)
Jenny Eclair(54 of100)
Alistair McGowan(55 of100)
Angelina Ballerina and Darcey Bussell(56 of100)
Konnie Huq(57 of100)
Kim Medcalf and Ade Edmondson(58 of100)
The Queen meets red nosers(59 of100)
Jack Dee's red nose stunt(60 of100)
Comic Relief USA, 2006(61 of100)
Kate Moss appears in the Little Britain live show...(62 of100)
...as does Russell Brand(63 of100)
Red nose capsules on the London Eye(64 of100)
Russell Brand, the Sugababes and Girls Aloud(65 of100)
Russell Brand and Lenny Henry(66 of100)
Sadie Frost(67 of100)
Sharon Osbourne(68 of100)
Gordon Brown and red nosers(69 of100)
Alastair Campbell(70 of100)
Ruth Jones, Rob Brydon and Joanna Page(71 of100)
Jo Brand and The Saturdays(72 of100)
David Tennant(73 of100)
Celebrity Strictly Come Dancing stars Rachel Stevens and Tom Chambers (74 of100)
Brian McLauchlin has an ice bath(75 of100)
Zoe Ball and Suggs(76 of100)
Captain Lars Gade Olesen and The King Of Scandinavia ferry(77 of100)
Number 10 gets another red nose(78 of100)
Gordon Brown with Cheryl Cole(79 of100)
Robbie Savage and his red-nosed Lamborghini(80 of100)
Caprice(81 of100)
Dick and Dom(82 of100)
A red nose gets carried up Skiddaw in the Lake District(83 of100)
Scotland's Ryan Krause and teammates(84 of100)
Lara Stone(85 of100)
Jimmy Carr and Al Murray(86 of100)
Dermot O'Leary and Kara Tointon on the Red Nose Desert Trek(87 of100)
Alex Salmond and fellow Scottish politicians(88 of100)
Miranda Hart, Emma Freud and Sanjeev Bhaskar (89 of100)
Clare Balding(90 of100)
Kirsty Allsopp and Richard Bacon(91 of100)
Dara O'Briain, Jack Whitehall and Jon Richardson perform the world's highest stand-up gig(92 of100)
Harry Styles and fans(93 of100)
The cast of Cats(94 of100)
Christine Bleakley and friend(95 of100)
Kim Wilde performs the world's highest gig(96 of100)
Famous ladies and their 'Tea Party With a Twist'(97 of100)
Samantha Cameron(98 of100)
One Direction and David Cameron(99 of100)
Emma Freud, Lenny Henry and co celebrate 25 years of Comic Relief(100 of100)