David Letterman(01 of30)
Open Image Modal"The Late Show with David Letterman"(02 of30)
Open Image ModalIn 1980, David was offered his own morning show on NBC, "The David Letterman Show", which garnered him two Emmys in the first year. And since the 1982 debut of "Late Night with David Letterman" he has been a fixture on late-night television. Today, David is the host of "The Late Show with David Letterman" and just this year he surpassed Johnny Carson for having the longest late-night hosting career. (credit:AP)
Ellen DeGeneres(03 of30)
Open Image Modal"The Ellen DeGeneres Show"(04 of30)
Open Image ModalAfter leaving her mark on "The Tonight Show", Ellen went on to star in two television sitcoms, "Ellen" and "The Ellen Show". She even provided the voice for Dory in the Disney animated film, "Finding Nemo". Today, she is the ever-popular host of her own daytime talk show, "The Ellen Degeneres Show", which has garnered her more than a dozen Emmys. (credit:YouTube.com)
Jay Leno(05 of30)
Open Image Modal"The Tonight Show with Jay Leno"(06 of30)
Open Image ModalIn 1992, when Johnny Carson stepped down as host of "The Tonight Show", he passed the torch to Jay Leno. As a long-time guest host, Jay took over with ease. Here, he chats with Olympic gymnast, Gabby Douglass, and First Lady, Michelle Obama. (credit:AP)
Roseanne Barr(07 of30)
Open Image Modal"Roseanne"(08 of30)
Open Image ModalIn her earliest appearance on the "The Tonight Show" Roseanne talked housewives and homemakers in her hilarious "domestic godess" bit. And it was the huge popularity of the act that led her to land her own ABC series "Roseanne", which she went on to win numerous awards for. (credit:YouTube.com)
Eddie Murphy(09 of30)
Open Image ModalEddie in "Tower Heist"(10 of30)
Open Image ModalToday, Eddie is one of America's top-grossing actors of all time and he's secured his spot at number ten on Comedy Central's list of the 100 Greatest Stand-ups of All Time. His filmography includes hit movies like "Beverly Hills Cop", "The Nutty Professor" series, "Dreamgirls" and so many more. Here, Eddie stars alongside Ben Stiller in one of his most recent films, "Tower Heist". (credit:AP)
Jerry Seinfeld(11 of30)
Open Image Modal"Seinfeld"(12 of30)
Open Image ModalAfter several years on the late-night television circuit, Jerry was able to successfully launch "Seinfeld", a sitcom he created with Larry David. The show first aired in 1989 and quickly became the most popular sitcom on American television. Here, Jerry Seinfeld stars opposite of Jason Alexander, in a quintessentially "Seinfeld" moment at the diner. (credit:YouTube.com)
Bill Maher(13 of30)
Open Image Modal"Real Time with Bill Maher"(14 of30)
Open Image ModalToday, Bill is widely known for his political satire and social commentary. In the years since he first appeared on "The Tonight Show" he's hosted the late-night political talk show "Politically Incorrect with Bill Maher" and, more recently, he launched "Real Time with Bill Maher" on HBO. (credit:YouTube.com)
Jim Carrey(15 of30)
Open Image ModalJim in "Liar Liar"(16 of30)
Open Image ModalIt was only a matter of time following his debut on "The Tonight Show" before Jim Carrey began landing big name TV and film roles. By 1994, Jim starred in "Ace Venture: Pet Detective" and from there his career took off. Here, Jim is at his best in his critically acclaimed role in "Liar, Liar". (credit:YouTube.com)
Joan Rivers(17 of30)
Open Image Modal"Joan in Fashion Police"(18 of30)
Open Image ModalWhen Joan left "The Tonight Show" for her own show on Fox in 1986, the relationship between the two friends quickly soured. In fact, once she left, Johnny never again spoke with Joan and her talk show was quickly cancelled. Today, Joan is well-known as a television host and for her celebrity fashion advice. Here, she poses with her "Fashion Police" co-star, Kelly Osbourne, left, and her daughter, Melissa Rivers, right. (credit:AP)
George Carlin(19 of30)
Open Image ModalGeorge Carlin Stand-up(20 of30)
Open Image ModalAfter making a name for himself as a guest host on "The Tonight Show", George went on to host the first-ever episode of "Saturday Night Live". Today, George is well-known for his Grammy Award winning stand-up comedy albums and his critically acclaimed HBO comedy specials. (credit:WikiMedia)
Andy Kaufman(21 of30)
Open Image ModalAndy in "Taxi"(22 of30)
Open Image ModalIt was Andy's Foreign Man character that landed him a role in ABC's 1978 sitcom, "Taxi". When producers of the show saw Andy's act, they had a part written into the show just for him. Here, Andy is in character as Latka alongside Danny DeVito in "Taxi". (credit:YouTube.com)
Steven Wright(23 of30)
Open Image ModalSteven Wright Stand-up(24 of30)
Open Image ModalThree years after he first made an impression on "The Tonight Show", Steven released his first comedy album, I Have A Pony, which was nominated for the Grammy Award for Best Comedy Album. The success of his first album landed him a coveted HBO special, which became one of the longest-running and most-requested shows of its kind. (credit:Getty)
Freddie Prinze(25 of30)
Open Image ModalFreddie Prinze got his biggest career break when he was asked to appear on "The Tonight Show" in 1973. He was the first young comedian to be asked to have a sit-down chat with Johnny after his first appearance, making Johnny's stamp of approval that much more impressive. And later, Freddie would go on to make several appearances on the show and even guest host while Johnny was vacationing. (credit:Getty)
Freddie in "Chico and the Man"(26 of30)
Open Image ModalLess than a year after his first performance on "The Tonight Show", Freddie landed the leading role in "Chico and the Man", a television sitcom on NBC, which was an instant hit with audiences. (credit:Youtube.com)
Garry Shandling(27 of30)
Open Image ModalGarry Shandling made his first appearance on the show in 1981, and although Johnny didn't invite Garry to chat after his first few stand-up acts, Garry went on to become a frequent guest host on the show. Here, Garry hosts one of more than fifty episodes of "The Tonight Show". (credit:YouTube.com)
Garry in "The Larry Sanders Show"(28 of30)
Open Image ModalJust a few years after his first appearance on "The Tonight Show", Garry went on to create and star in his own show, "It's The Garry Shandling Show". But his biggest success was the "Larry Sanders Show", which he launched in 1992 and was based on Garry's experiences co-hosting "The Tonight Show". (credit:YouTube.com)
Louie Anderson(29 of30)
Open Image ModalLouie Anderson made his network television debut when he first stepped out on "The Tonight Show" stage in 1981. Having made the rounds as a stand-up comedian, it was only a matter of time before Louie would create his own Emmy Award winning role. (credit:Getty)
Louie on "Family Feud"(30 of30)
Open Image ModalIn 1995, Louie launched the animated Saturday morning show, "My Life With Louie", which was based on his experienced growing up in a big family. The show was a huge hit and went on to land Louie a Daytime Emmy. Later, he assumed the role of host on the newly revised version of the game show, "Family Feud". (credit:YouTube.com)