Sadly, no more can be done for the former pub landlady, and she prepares to say goodbye to her family, and Albert Square, for the final time.
When news reaches Grant, the thought of losing his mother brings his back to the Square - which also means he’ll come face-to-face with his brother Phil again.
A lot has changed since Grant was last in Walford, back in 2006.
He’ll also be faced with meeting Sharon Rickman and Kathy Beale again. We love Grant, but this ‘EastEnders’, so don’t expect everything to go without a hitch…
Watch ‘EastEnders’ from Monday 9 May to see the Mitchell family reunions begin. Catch up on all the latest soap news and spoilers here.
Everything We Know About Peggy Mitchell's 'EastEnders' Return
When does Peggy die?(01 of06)
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Having returned to the Square on Monday 9 May, the much-loved character will make her last ever appearance on Tuesday 17 May, in what is bound to be some of the soap's most emotional scenes ever. (credit:BBC Pictures)
What's the storyline?(02 of06)
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For those of you who need a refresher, here's what's happening: Peggy made a brief appearance in January, revealing that her cancer is back.
This month, viewers will see her decide to decline treatment, opting to enjoy the time she has left with her family. Though as you can imagine, this decision does not go down well with Phil. (credit:BBC Pictures)
Is Ross Kemp also returning?(03 of06)
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YES! You didn't think Grant would miss the chance to say a final goodbye to his mum, surely? (credit:Neil Mockford/Alex Huckle via Getty Images)
Who else is back?(04 of06)
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Danniella Westbrook is also reprising her role as Sam Mitchell. (credit:Alex Huckle via Getty Images)
Will it be emotional?(05 of06)
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Without a doubt. Soap boss Dominic Treadwell Collins has said: Barbara gives the performance of her lifetime. Her last episode will break your heart. It genuinely, genuinely will break your heart." Tissues at the ready... (credit:BBC Pictures)
Will there be any surprises?(06 of06)
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Bosses are obviously remaining tight-lipped on the exact details of how things will develop, but we reckon they're bound to have a few secrets up their sleeves.
Anyone in doubt need only cast their minds back to live week's Kathy Beale reveal. (credit:BBC Pictures)